Richard Slayman, the 62-year-old who made historical past by receiving the world’s first genetically modified pig kidney transplant in March, has died, his household introduced on Saturday.
Mr Slayman underwent the profitable four-hour surgical procedure at Massachusetts Normal Hospital and was launched simply two weeks later in April. Whereas the reason for his sudden demise stays unknown, the hospital has confirmed it was not associated to the transplant, ABC Information reported.
“The Mass Normal transplant workforce is deeply saddened on the sudden passing of Mr. Rick Slayman. We’ve no indication that it was the results of his current transplant,” Massachusetts Normal Hospital stated in an announcement.
Richard Slayman, a resident of Weymouth, Massachusetts, had battled Kind 2 diabetes and hypertension for years earlier than receiving the transplant. Earlier than the groundbreaking pig kidney transplant, Mr Slayman had an extended historical past of managing Kind 2 diabetes and hypertension. He additionally relied on dialysis for a number of years earlier than receiving a human kidney transplant in December 2018, carried out by the identical Massachusetts Normal Hospital workforce.
Sadly, the transplanted kidney from the human donor functioned for about 5 years earlier than exhibiting indicators of rejection. In Might 2023, Mr. Slayman needed to return to dialysis remedy, which considerably impacted his high quality of life, in line with the hospital.
“Mr. Slayman will eternally be seen as a beacon of hope to numerous transplant sufferers worldwide and we’re deeply grateful for his belief and willingness to advance the sector of xenotransplantation. We provide our heartfelt condolences to Mr Slayman’s household and family members as they keep in mind a rare particular person whose generosity and kindness touched all who knew him,” the hospital’s assertion learn.
The kidney used within the transplant got here from eGenesis, a Cambridge-based pharmaceutical firm. This pioneering organ was harvested from a pig genetically modified utilizing CRISPR-Cas9 expertise. Based on Massachusetts Normal Hospital, the modification course of concerned eradicating incompatible pig genes and introducing particular human genes to reinforce compatibility with the recipient’s physique.
In a heartfelt assertion, Mr Slayman’s household expressed their deepest appreciation to the docs and all the care workforce at Massachusetts Normal Hospital.
“Our household is deeply saddened concerning the sudden passing of our beloved Rick however take nice consolation understanding he impressed so many. Thousands and thousands of individuals worldwide have come to know Rick’s story. We felt – and nonetheless really feel – comforted by the optimism he supplied sufferers desperately ready for a transplant.”
“We’re extraordinarily grateful to his care workforce throughout Massachusetts Normal Hospital and Mass Normal Brigham, particularly Dr Williams, Dr Kawai, and Dr Riella, who actually did all the things they may to assist in giving Rick a second probability. Their huge efforts main the xenotransplant gave our household seven extra weeks with Rick, and our reminiscences made throughout that point will stay in our minds and hearts.”
Mr Slayman’s household revealed that certainly one of his driving forces behind the transplant was the will to supply hope to the numerous people battling end-stage organ failure and desperately ready for a lifesaving transplant.
“Rick completed that aim and his hope and optimism will endure eternally. His legacy will likely be one which evokes sufferers, researchers, and well being care professionals all over the place.”