Biohacker and tech entrepreneur Bryan Johnson has been recognized to push the boundaries relating to experimenting with longevity. In one in all his current makes an attempt, he turned to hyperbaric oxygen remedy (HBOT) — a remedy initially used to help wound therapeutic and deal with decompression illness. Sharing his expertise on Instagram, Bryan mentioned, “I spent 5,400 minutes in a pressurised tank, so that you don’t have to determine how hyperbaric oxygen remedy works. It’s a remedy that’s used with elite athletes and stroke sufferers. However it’s additionally a cutting-edge remedy for longevity.”
He provides, “You sit in a pressurised chamber, respiratory pure oxygen. That additional oxygen might enhance therapeutic, increase efficiency, and will enhance longevity. That is what I got down to do — 60 classes in 90 days. The outcomes have been higher than I anticipated. Among the extra noteworthy outcomes is that my blood ranges got here again and confirmed I had no detectable ranges of irritation, a marker for cognitive decline, Alzheimer’s decreased by 28.6%. My microbiome improved dramatically. My pores and skin well being dramatically improved and my telomere lengthened. This can be probably the most efficacious entire physique rejuvenation remedy I’ve ever finished.”
However is it actually efficient for longevity?
Dr Gunasekar Vuppalapati MBBS, MS, FRCSEd, MCh, senior reconstructive, aesthetic plastic surgeon at GVG Invivo Hospitals and Apollo Hospitals, tells indianexpress.com, “Hyperbaric Oxygen Remedy (HBOT) entails respiratory pure oxygen in a pressurised chamber, permitting the additional oxygen to dissolve within the plasma, which is then circulated all through the physique. Virtually, this will increase the oxygen focus out there to each cell within the physique, enhancing tissue restore and supporting therapeutic processes attributable to decreased capillary density, peripheral blood perfusion, mobile oxygenation ultimately organs resembling extremities, kidneys, retina and so on.”
In the case of longevity or broad mobile restore in wholesome people, he says, the proof was minimal and largely anecdotal till the yr 2020, when potential trial outcomes have been revealed from Telaviv College, Israel, within the Nationwide Library of Medication. “This breakthrough research titled ‘Hyperbaric oxygen remedy will increase telomere size and reduces immunosenescence in remoted blood cells: a potential trial’ concluded that HBOT might induce vital senolytic results, together with considerably rising telomere size and clearance of senescent cells within the ageing populations. Nonetheless, long-term research are required to find out the extent to which the lifespan and/or healthspan will be prolonged with HBOT as a supplementary remedy alongside the opposite regenerative anti-aging measures to gradual the ageing course of,” Dr Vuppalapati notes.
Potential dangers or unwanted side effects
For in any other case wholesome people, Dr Vuppalapati says, present process 60 classes of HBOT in simply three months is sort of intensive. “Whereas HBOT is usually protected when administered below medical supervision, repeated publicity at such frequency can carry sure dangers.”
He provides, “Recognized unwanted side effects embrace ear barotrauma (pressure-related ear ache or damage), sinus discomfort, and short-term imaginative and prescient modifications like nearsightedness. Some people might expertise oxygen toxicity, significantly with extended high-dose publicity, which might have an effect on the central nervous system or lungs. Nonetheless, that is very uncommon, except the remedy exceeds the security limits regarding strain, the length, and the required weekly breaks prescribed; and if finished by unqualified personnel in services with no license.”
There’s additionally a theoretical danger that extreme oxidative stress, he asserts, attributable to very excessive oxygen ranges, might result in mobile injury over time, significantly in somebody with no medical want for the remedy. “As clinicians, we at all times advocate for a measured and medically indicated method to HBOT quite than overuse with out clear profit,” states the professional.
DISCLAIMER: This text is predicated on data from the general public area and/or the specialists we spoke to. All the time seek the advice of your well being practitioner earlier than beginning any routine.